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Odyssey Therapeutics

The business, the turning points, and the decisions behind them.

FundingUS$101.6M
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Sections to complete:02 · 05

01 / WHAT IT BUILT

What the company did

Odyssey Therapeutics is a Boston-based clinical-stage biotech focused on autoimmune and inflammatory diseases, founded and led by Gary Glick, Ph.D. Its pipeline is led by a RIPK2 inhibitor (OD-07656/OD-001) being readied for phase 2 trials for ulcerative colitis as a monotherapy and in combination with Takeda's Entyvio. It built its assets and capabilities through deals — buying Rahko for machine learning and IFM Discovery (a subsidiary of IFM Therapeutics, also founded by Glick) for MDA5 and NLRP1 discovery programs — and through Big Pharma partnerships, including $6.5 million from Johnson & Johnson for AI-driven small-molecule discovery and $1 million from Pfizer for natural-product hit finding. In September 2025 it closed a $213 million Series D, and after withdrawing a January 2025 IPO attempt, it went public on Nasdaq in May 2026 (ticker ODTX), raising around $279–304 million in an upsized IPO and concurrent private placement. No shutdown, bankruptcy, or acquisition has been publicly documented.

02 / FAILURE REASONS

Pending assessment

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03 / EVENT HISTORY

Events in the structured record

  1. IPO withdrawn

    In January 2025, Odyssey filed for an IPO but withdrew its registration statement, saying the offering was not in the company's best interests at the time.

  2. Raised $213M Series D

    In September 2025, Odyssey closed a $213 million Series D to finance clinical proof-of-concept studies and its discovery pipeline.

  3. Nasdaq IPO

    In May 2026, Odyssey went public on Nasdaq (ticker ODTX), raising around $279-304 million in an upsized IPO and concurrent private placement.

04 / CONTEMPORARY REBUILD ASSESSMENT

Difficulty of rebuilding this project today

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Rebuild difficultyPending assessmentNot completed
Scoring basisNot completed
ScalabilityPending assessmentNot completed
Scoring basisNot completed

Overall assessment: Not completed

05 / CAUSAL CHAIN / AFTERMATH

Pending assessment

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